New Drug May Offer Ways To Tame Menopause

Since it was discovered that the risks of hormone therapy outweighed the benefits, scientists have been searching for a safe, natural way to alleviate the symptoms of menopause.

Participants are currently being recruited for a follow-up clinical trial of a treatment known as MF101 developed by Bionovo, Inc. In its initial clinical trial, MF101 provided women in the study with preliminary evidence of relief from such symptoms as hot flashes and night sweats, without the risks associated with hormone therapy.

The treatment being tested clinically targets only one of the two known estrogen receptors-the estrogen receptor beta. Laboratory data has shown that MF101 does not cause the proliferation of breast or uterine cancer cells the way hormone therapy can, making the drug a safer alternative to currently available hormone therapies.

In 2002, the Women’s Health Initiative (WHI) Estrogen Plus Progestin Trial, with over 16,000 women participants, was stopped early when it was found that the standard dose of combination hormone therapy increased the risk of breast cancer, stroke, heart attacks, blood clots and dementia.

“Given the void that exists for a safe and effective treatment for menopausal symptoms, our aim is to discover and develop novel drugs such as MF101 that can abate many of the symptoms that have historically been treated with hormones,” said Dr. Mary Tagliaferri. Tagliaferri is co-author of “The New Menopause Book: The Experts Help You Make Informed Decisions on HRT, Natural Hormone Therapy, Herbal Therapies, Traditional Chinese Medicine And More” (Avery, 2006) and Chief Medical Officer of Bionovo, which is developing the drug.

The clinical trials will take place under the directorship of renowned researcher Dr. Deborah Grady at four leading academic medical centers.

Bionovo expects this Phase 2 trial to be completed by the second quarter of 2007.

“If this new drug proves to be effective, we will be providing health care practitioners with a treatment they can comfortably recommend to women experiencing menopause,” said Dr. Tagliaferri.

Why Must Your Business Hire an Order-Taking Service?

Business firms that offer propelled client administration will probably produce more wage and secure their positions in the market when contrasted with the individuals who don’t. Also, this is the motivation behind why most organizations and business elements frequently discover more courses just to upgrade their client connections. These connections could all the more be braced by guaranteeing that customers are being esteemed and gone to.

The interests of the clients are the fundamental worry of the administration arranged firms. Business pioneers need to be sure that the requirements of the buyers are met and they are happy with the items and administrations that they offer. Regardless, there might be times wherein fulfilling those necessities can in reality be excessively troublesome particularly for a growing firm which as of now has a lot of clients however just does not have the required human funding to take into account the perpetually developing needs of their customers. These basic needs include setting orders.

At the point when customers call to have their requests, organizations need to guarantee that there’s dependably somebody accessible to pick the telephone and reply to them; an unanswered call implies another lost deals opportunity. Clearly, no chief or entrepreneur needs to ever lose any business openings. Along these lines, the best way to keep this from happening is to allot an individual from the staff to take orders from customers.

A successful answer for this test is to utilize a live request taking administration. Business firms which use this apparatus ensure that requests are being gotten and handled by the staff and all the more imperatively, all calls are being replied.

Business foundations like in retail and those in the sustenance enterprises, for example, eateries got high approaching call volumes constantly. This is on account of individuals get in touch with them for the most part either to put in their requests or basically to get some information about their item or administration. Most as a rule, these organizations just got a couple staff in their association and there is really no allocated individual to bear at work of taking requests. Servers, agents or even chiefs answer to telephone calls in the event that they need to. This is the motivation behind why a standard working day in these sorts of business ventures could be disordered and constantly boisterous.

Most business visionaries can state that a live request taking administration is truly not that critical especially for those organizations who as of now have their sites and offer online request taking frameworks. Be that as it may, gone ahead, on the off chance that you are being practical about it, purchasers will dependably have request as a main priority and it is not quite recently about putting in their requests. Also the way that run of the mill clients or customers lean toward (and they feel quiet) to converse with a live individual. While online frameworks are simple and fast, they likewise have their comparing downsides. As yet, nothing beats human correspondence and that is the thing that a live request taking individual could give.

New Technology For Immediately Refreshing Your Appearance

Ladies all know that no matter how much makeup we wear of how carefully and strategically we apply it before we leave the house, often times it’s almost gone by the time we get to the office. And, we might as well forget about it by lunch or quitting time.

Traditionally our midday and end-of-day touch-ups were part of our daily routine. But, now, according to experts, instead of women sneaking off into the washroom for a quick (facial) pick-me-up, they are sneaking instead into the spa or doctor’s office.

It’s all part of the latest trend of non-invasive mini-facelifts, wrinkle elimination and waistline reduction procedures commonly referred to a “lunchtime plastic surgeries”.
And, experts assert that lots of patients want immediate and measurable results and without going under the knife.

Among the most common procedures (gaining in popularity) are suture lifts. Suture lifts or Lifestyle Lifts are noted as being ideal for those on a budget and are described as one-hour, in-office microsurgeries that involve strategically situated surgical threads administered under local anesthetic. Lifestyle Lifts are done in order to firm the lower face and neck area by placing tiny, permanent sutures under the skin to lift and tighten sagging muscles.

Contour Threads is another procedure geared toward a droopy brow, cheek or jowl, and involves passing a needle and barbed thread beneath loose skin and tugging it back into place, offering natural and instantaneous results.

The Lifestyle lift is said to last between 5 and 20 years and Contour Thread for between three and five years. And, outside of some (minor) swelling and bruising, you can expect to recover (from either procedure) within a few days (especially if you use an ice pack.

The only “drawbacks”, according to experts is that Lifestyle Lifts offer the greatest benefit and results to women over 40; and Contour Threads can be performed on younger women but won’t last as long as the Lifestyle lift or a traditional facelift.

Why You Should Use Personal Assistant Service

In the event that you lean toward having a locally established business with a base capital, you might need to set up an individual collaborator benefit business. Individuals occupied with this business give individual help to other individuals with their every day life exercises. You may likewise serve an establishment or business organization as their own aide. Along these lines, you help the organization with expanded effectiveness and efficiency.

Giving a support of a private individual, big name, government official or to anybody regularly obliges you to do errands for them, for example, dealing with a logbook or calendars, making travel courses of action, shopping, speaking with other individuals for their benefit, investigating, occasion arranging, and different errands that they have to pass on to a colleague.

Then again, giving an individual aide administration to an organization or business organization obliges you to be an authoritative master. A portion of the obligations that might be required for you to fulfill are as per the following: answer telephone calls from customers, oversee and react to messages, deal with essential messages from spam, oversee logbook, do online research, gets ready composed archives, oversee web-based social networking, travel courses of action, book inns and flights, get ready organization profiles, thus numerous different obligations.

Before beginning this administration, you need to think of some as variables. To begin with, settle on what administrations you will offer. You may confine your administrations amid the initial couple of months, at that point extend it when you get used to the intricate details of your business. Next, process on your cost. You have to check your charges on each administration sort that you give. Likewise, decide on how you wish to be paid. You have the alternative to charge customers through hourly rate, level rate, or even mileage rate which might be connected when you go out for an errand to be refined. In conclusion, set up your own particular site. This will fill in as your advertising arm in discovering customers. Moreover, it fills in as your profile portfolio. Along these lines, your achievements will be recorded that may assist persuade your future customers to get your administration.