New Drug May Offer Ways To Tame Menopause

Since it was discovered that the risks of hormone therapy outweighed the benefits, scientists have been searching for a safe, natural way to alleviate the symptoms of menopause.

Participants are currently being recruited for a follow-up clinical trial of a treatment known as MF101 developed by Bionovo, Inc. In its initial clinical trial, MF101 provided women in the study with preliminary evidence of relief from such symptoms as hot flashes and night sweats, without the risks associated with hormone therapy.

The treatment being tested clinically targets only one of the two known estrogen receptors-the estrogen receptor beta. Laboratory data has shown that MF101 does not cause the proliferation of breast or uterine cancer cells the way hormone therapy can, making the drug a safer alternative to currently available hormone therapies.

In 2002, the Women’s Health Initiative (WHI) Estrogen Plus Progestin Trial, with over 16,000 women participants, was stopped early when it was found that the standard dose of combination hormone therapy increased the risk of breast cancer, stroke, heart attacks, blood clots and dementia.

“Given the void that exists for a safe and effective treatment for menopausal symptoms, our aim is to discover and develop novel drugs such as MF101 that can abate many of the symptoms that have historically been treated with hormones,” said Dr. Mary Tagliaferri. Tagliaferri is co-author of “The New Menopause Book: The Experts Help You Make Informed Decisions on HRT, Natural Hormone Therapy, Herbal Therapies, Traditional Chinese Medicine And More” (Avery, 2006) and Chief Medical Officer of Bionovo, which is developing the drug.

The clinical trials will take place under the directorship of renowned researcher Dr. Deborah Grady at four leading academic medical centers.

Bionovo expects this Phase 2 trial to be completed by the second quarter of 2007.

“If this new drug proves to be effective, we will be providing health care practitioners with a treatment they can comfortably recommend to women experiencing menopause,” said Dr. Tagliaferri.

Why Must Your Business Hire an Order-Taking Service?

Business firms that offer propelled client administration will probably produce more wage and secure their positions in the market when contrasted with the individuals who don’t. Also, this is the motivation behind why most organizations and business elements frequently discover more courses just to upgrade their client connections. These connections could all the more be braced by guaranteeing that customers are being esteemed and gone to.

The interests of the clients are the fundamental worry of the administration arranged firms. Business pioneers need to be sure that the requirements of the buyers are met and they are happy with the items and administrations that they offer. Regardless, there might be times wherein fulfilling those necessities can in reality be excessively troublesome particularly for a growing firm which as of now has a lot of clients however just does not have the required human funding to take into account the perpetually developing needs of their customers. These basic needs include setting orders.

At the point when customers call to have their requests, organizations need to guarantee that there’s dependably somebody accessible to pick the telephone and reply to them; an unanswered call implies another lost deals opportunity. Clearly, no chief or entrepreneur needs to ever lose any business openings. Along these lines, the best way to keep this from happening is to allot an individual from the staff to take orders from customers.

A successful answer for this test is to utilize a live request taking administration. Business firms which use this apparatus ensure that requests are being gotten and handled by the staff and all the more imperatively, all calls are being replied.

Business foundations like in retail and those in the sustenance enterprises, for example, eateries got high approaching call volumes constantly. This is on account of individuals get in touch with them for the most part either to put in their requests or basically to get some information about their item or administration. Most as a rule, these organizations just got a couple staff in their association and there is really no allocated individual to bear at work of taking requests. Servers, agents or even chiefs answer to telephone calls in the event that they need to. This is the motivation behind why a standard working day in these sorts of business ventures could be disordered and constantly boisterous.

Most business visionaries can state that a live request taking administration is truly not that critical especially for those organizations who as of now have their sites and offer online request taking frameworks. Be that as it may, gone ahead, on the off chance that you are being practical about it, purchasers will dependably have request as a main priority and it is not quite recently about putting in their requests. Also the way that run of the mill clients or customers lean toward (and they feel quiet) to converse with a live individual. While online frameworks are simple and fast, they likewise have their comparing downsides. As yet, nothing beats human correspondence and that is the thing that a live request taking individual could give.

New Technology For Immediately Refreshing Your Appearance

Ladies all know that no matter how much makeup we wear of how carefully and strategically we apply it before we leave the house, often times it’s almost gone by the time we get to the office. And, we might as well forget about it by lunch or quitting time.

Traditionally our midday and end-of-day touch-ups were part of our daily routine. But, now, according to experts, instead of women sneaking off into the washroom for a quick (facial) pick-me-up, they are sneaking instead into the spa or doctor’s office.

It’s all part of the latest trend of non-invasive mini-facelifts, wrinkle elimination and waistline reduction procedures commonly referred to a “lunchtime plastic surgeries”.
And, experts assert that lots of patients want immediate and measurable results and without going under the knife.

Among the most common procedures (gaining in popularity) are suture lifts. Suture lifts or Lifestyle Lifts are noted as being ideal for those on a budget and are described as one-hour, in-office microsurgeries that involve strategically situated surgical threads administered under local anesthetic. Lifestyle Lifts are done in order to firm the lower face and neck area by placing tiny, permanent sutures under the skin to lift and tighten sagging muscles.

Contour Threads is another procedure geared toward a droopy brow, cheek or jowl, and involves passing a needle and barbed thread beneath loose skin and tugging it back into place, offering natural and instantaneous results.

The Lifestyle lift is said to last between 5 and 20 years and Contour Thread for between three and five years. And, outside of some (minor) swelling and bruising, you can expect to recover (from either procedure) within a few days (especially if you use an ice pack.

The only “drawbacks”, according to experts is that Lifestyle Lifts offer the greatest benefit and results to women over 40; and Contour Threads can be performed on younger women but won’t last as long as the Lifestyle lift or a traditional facelift.

Why You Should Use Personal Assistant Service

In the event that you lean toward having a locally established business with a base capital, you might need to set up an individual collaborator benefit business. Individuals occupied with this business give individual help to other individuals with their every day life exercises. You may likewise serve an establishment or business organization as their own aide. Along these lines, you help the organization with expanded effectiveness and efficiency.

Giving a support of a private individual, big name, government official or to anybody regularly obliges you to do errands for them, for example, dealing with a logbook or calendars, making travel courses of action, shopping, speaking with other individuals for their benefit, investigating, occasion arranging, and different errands that they have to pass on to a colleague.

Then again, giving an individual aide administration to an organization or business organization obliges you to be an authoritative master. A portion of the obligations that might be required for you to fulfill are as per the following: answer telephone calls from customers, oversee and react to messages, deal with essential messages from spam, oversee logbook, do online research, gets ready composed archives, oversee web-based social networking, travel courses of action, book inns and flights, get ready organization profiles, thus numerous different obligations.

Before beginning this administration, you need to think of some as variables. To begin with, settle on what administrations you will offer. You may confine your administrations amid the initial couple of months, at that point extend it when you get used to the intricate details of your business. Next, process on your cost. You have to check your charges on each administration sort that you give. Likewise, decide on how you wish to be paid. You have the alternative to charge customers through hourly rate, level rate, or even mileage rate which might be connected when you go out for an errand to be refined. In conclusion, set up your own particular site. This will fill in as your advertising arm in discovering customers. Moreover, it fills in as your profile portfolio. Along these lines, your achievements will be recorded that may assist persuade your future customers to get your administration.

Menopause Discover How To Control The Symptoms.

While menopause is a normal change in life that all women experience, the symptoms can be extremely bothersome. Some women are bombarded with these uncomfortable symptoms, and search out ways to help control them. Here we will discuss menopause and how to help control its symptoms.

Hot flashes are one of the most common symptoms of menopause. Hot flashes are also known as night sweats, but do not always occur at night. It is when your body becomes suddenly hot, so hot, that it radiates into the face and neck area. Very often the person suffering with the hot flash will sweat so profusely that the sweat will saturate her clothing. A hot flash is usually always followed by a chill, or cooling down period. To help control hot flashes effectively, a woman can add soy products or more fiber to her diet.

Vaginal dryness is another uncomfortable symptom of menopause. Research studies have shown that adding vitamin E supplements to their daily routines, many women have lessened, and even eliminated vaginal dryness all together. Vitamin E suppositories are available for menopausal women – these are inserted into the vagina. Vitamin E is also proven effective in aiding in the reduction, or even elimination, of hot flashes, as well.

There are numerous natural remedies to help in controlling many of the symptoms of menopause. Due to lack of hormones being produced in their bodies, many women will experience bouts of moodiness, and sometimes even depression. St. John’s Wart, which can be purchased at many health food stores, can often help with this. By adding a St. John’s Wart supplement to their daily routine, many women have reported being less irritable, less depressed, and even energized. Other supplements that can help with moodiness include kava kava and valerian.

Black cohosh is a very popular herb women use to help cut down on the symptoms of menopause. Black cohosh can help with hot flashes, cramps, and heavy menstrual bleeding. Research studies have also shown that black cohosh may even help prevent osteoporosis. Most research studies recommend you take black cohosh extract, and it may take two to four weeks before noticed results occur.

Like black cohosh, chasterberry (or vitex agnus castus) can help alleviate symptoms of menopause including hot flashes and vaginal dryness. In addition to these symptoms of menopause, chasterberry may also help with breast tenderness. Women have reported it taking up to four weeks to achieve noticeable results.

While the symptoms of menopause can be uncomfortable, bothersome, and irritating, there is hope. In addition to traditional hormone replacement therapy, many options are available to help lessen, or even eliminate the symptoms of menopause.

Is Laser Hair Treatment Worth A Try?

With special mention to the various technologies of today, the usual unattended abnormalities for human features are slowly being given emphasis, one of which is Hair Removal. Excessive hair in various parts of the human body have become a bane for most people, especially the females, who have to resort to the traditional ways of taking out unwanted hair from their bodies. With the fruits of technology vastly being developed, such issues have been given the proper study and treatments have become numerous and welcome to people who consider such discomforts something critical in their daily lives, especially for people who are very much particular about their appearance.

Hereditary Growth Issues and Abnormal Growth

People expect to land some hereditary traits passed on from their genes, and hair growth is something that goes along with this. All people, from teenagers to the adults consider such traits as a bane, having to attend to them regularly and take out these unwanted hair growth. Many have tried various techniques presented, largely manual means and taking medically developed chemicals to be able to prevent excessive hair growth, but these have not proven to be effective, especially for people who are quite particular about time consumption from their daily lives. They have to allot a certain period of their day towards doing these manual and temporary ways of hair removal just to be able to satisfy what they want to project when they interact daily.

Laser Hair Removal

Laser hair removal has provided the consumers with a technology-developed means of being able to answer one of their bodily concerns. There is not control that such hair growth issues can be answered through the use of the manual means of medication or practices. At first glance, laser removal may be considered as a painful process to the clueless people of today, but in reality, laser hair removal is truly a pain-less procedure. Perhaps the only painful thing about it is the costs that are involved but the benefits after undergoing such a procedure will help most consumers use that small time for something more worthwhile.

The procedure itself depends on the part of the body, which it shall be made. For example, an entire back can be done in 1 to 2 minutes or an upper lip in less than 10 seconds. Not bad considering that a lifetime of grief can be treated in such a short span of time.

People who seek Hair Removal

1. Teenagers are in the period of transition where they are becoming more aware and conscious of their physical appearance. This especially holds true towards the female population. While some hormones may find some women having excessive hair on their legs, armpits and lips, these can be answered by laser hair treatment.

2. Ordinarily, all males would prefer to have excessive hair in most parts of their body to retain that macho man look. For some however, the definition of excess hair may not sit well. The male population as well, seeks laser hair medical treatment for one reason or another, like for athletes; comfort is their most common reason for having such excessive hair removed to be able to perform up to par in the competitions they participate in.

3. Not to be left out, pregnant ladies can expect excessive hair growth during their time of pregnancy. This is not an abnormal occurrence; it is natural in the sense that the sex hormones known as androgens are increased in the first trimester of the pregnancy periods. Applying laser hair removal is considered safe, but however painful at this stage due to the load that they already bear while they are in this stage. However, all these excessive hair growth are expected to disappear three to six months after giving birth.

Permanent Hair Removal

For most people who are tired of having to concern themselves with the excessive and abnormal growth of hair in various parts of their bodies, a permanent solution would be their immediate choice. Painless but costly, such a procedure would rid them of such problems and this would in turn be something worth their investment. Instead of having to rely on the temporary means of being able, to remove these unwanted hair growth in various parts of the body. Most people look towards permanent hair removal, and this is something that is really more realistic, especially for people who don’t want to be able to be burdened by minor problems as having to be bothered by hair growth. Permanent laser hair removal, expensive as it may seem but less painful serves as the logical answer to most people, who consider abnormal hair growth an issue for them.

Menopause and Gastrointestinal Distress

Numerous women report that menopause comes along with gastrointestinal distress causing uncomfortable symptoms such as indigestion, flatulence and sudden bloating. Not only are these annoying and embarrassing, they can also be quite painful.

During menopause, gastrointestinal bloating is caused when air fills the abdomen, creating a full feeling. Even though your stomach remains the same size, your pants probably feel tighter and your waistline just seems to keep expanding. Excess intestinal gas is produced by bacteria in the intestines. Sugar located foods often contribute to the growth of this bacterium.

Poor digestion, a lack of lactose – an enzyme that breaks down food and liquids, can cause gastrointestinal distress as well. Gas distress can also be rampant during menopause due to lack of estrogen. Medical studies have suggested that a menopausal woman’s diet can be to blame – particularly too many high sugar foods including fruit, and certain vegetables such as cauliflower, onion and broccoli that create even more bacteria in already inflamed intestines.

Of course your hormones might also be the trigger for bloating. For example, progesterone in the right doses has a calming effect, but in too high doses can cause bloating and breast tenderness. A form of estrogen called Estradiol, on the other hand, is sometimes prescribed as a relief for bloating.

People who eat too much protein at once can cause bloating because the stomach can’t digest it all. Enzymes that help digestion such as Beano aid in the consumption of products such as soy that can have numerous positive effects for menopausal women.

Herbs can be used to restore balance in menopause. You need to be clear on what stage of menopause you are in. Different hormone levels vary significantly from peri-menopause to menopause and post-menopause, and of course your doctor needs to help you with these decisions.

For bloating as well as headaches and breast tenderness, an herbal tea that provides minerals in a dissolved form can help. Minerals help your body handle waste loads as well as provide a good source of calcium. You can use a combination of raspberry, dandelion, lemon balm, nettles, and green oat straw tea. Drink one cup of tea per day. Don quai can increase the effectiveness of estrogen released from fat tissue and help soothe menopausal discomfort as well.

The information in this article is for educational purposes only, and is not intended as medical advice.